It works by changing the actions of chemicals in your brain. Trifluoperazine is used to treat anxiety or psychotic disorders such as schizophrenia. Trifluoperazine may also be used for purposes not listed in this medication guide.

Certificate of Analysis

• Description

  A White to pale yellow Crystalline powder, odourless, slightly Hygroscopic.

  Result

  White powder Odourless.

• Solubility

  Freely soluble in water soluble in alcohol.

  Result

  Complies

• Melting point

  It melts at about 242° C with decomposition.

  Result

  Complies

• pH (10 % w/w)

  1.7 to 2.6

  Result

  1.85

• Identification by UV/VIS

  Should gave specifica bsorbance maximum at 256 nm.

  Result

  Complies

• Identification by IR

  To Comply

  Result

  Complies

• Identification By TLC (Phenothiazines test)

  To Comply

  Result

  Complies

• Identification by Chemical Test

  Should Orange colour develops

  Result

  Complies

• Identification by Test of Chlorides

  Should respond to the Chloride

  Result

  Complies

• Sulphated ash

  Not more than 0.1 %

  Result

  0.05 % w/w

• Loss on drying

  Not more than 1.0 %

  Result

  0.29 % w/w

• Related substances (By TLC)

  Should comply.

  Result

  Complies

• Assay

  Not more than 99.0 % / Not more than 101.0 % w/w calculated on dried basis.

  Result

  99.77 % w/w

Note: Note: – We are leading channel partner of much API manufacturer, supplier & exporters and Pharmaceutical raw material in Colombo, Chili, Ecuador and Globally.

Material Safety Data Sheet

• Section 1 – Chemical Product

  Product Identifier

  Trifluoperazine HCL

  MSDS Prepared By

  R&D Department

• Section 2 – Composition / Information Of Ingredients

  Product Name

  Trifluoperazine Hydrochloride

  Synonym

  10-(3-(4-Methyl-1-piperazinyl)propyl)-2- trifluoromethylphenorhiazine dihydrochloride; Eskazine; Fluoperazine; Stelazine; Terfluzine; Trifluoperazine dihydrochloride; Trifluopyrazin dihydrochloride;Trifluperazine dihydrochloride; Triftazin; Triphthazine; Triphthazine dihydrochloride; tryptazine; Tryptazine dihydrochloride

  Molecular Formula

  C21-H24-F3-N3-S.2HCl

  Molecular Weight

  480.43 g/mole

  CAS Number

  440-17-5

• Section 3 – HAZARDOUS IDENTIFICATION

  Potential Acute Health Effects

  Hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, of inhalation.

  Potential Chronic Health Effects

  Carcinogenic Effects

  N/A

  Mutagenic Effects

  N/A

  Teratogenic Effects

  N/A

  Development Toxicity

  Not available. Repeated or prolonged exposure is not known to aggravate medical condition.

• Section 4 – FIRST AID

  Skin Contact

  In case of contact, immediately flush skin with plenty of water. Cover the irritated skin with an emollient. Remove contaminated clothing and shoes. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention.

  Serious Skin Contact

  Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek immediate medical attention.

  Eye Contact

  Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical attention.

  Inhalation

  If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.

  Ingestion

  Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight clothing such as a collar, tie, belt or waistband.

• Section 5 – FIRE FIGHTING MEASURES

  Flammability of the Product

  May be combustible at high temperature.

  Auto-ignition Temperature

  N/A

  Flash Points

  CLOSED CUP: Higher than 93.3°C (200°F).

  Flammable Limits

  N/A

  Products of Combustion

  These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2…), sulphur oxides (SO2, SO3…), halogenated compounds.

  Fire Hazards in Presence of Various Substances

  Slightly flammable to flammable in presence of heat.

  Explosion Hazards in Presence of Various Substances

  Risks of explosion of the product in presence of mechanical impact

  N/A

  Risks of explosion of the product in presence of static discharge

  N/A

  Fire Fighting Media and Instructions

  Small Fire

  Use DRY chemical powder.

  Large Fire

  Use water spray, fog or foam. Do not use water jet.

  Special Remarks on Fire Hazards

  N/A

  Special Remarks on Explosion Hazards

  N/A

• Section 6 – ACCIDENT RELEASE MEASURES

  Small Spill

  Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements.

  Large Spill

  Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate through the sanitary system.

• Section 7 – HANDLING AND STORAGE

  Precautions for Handling

  Keep away from heat. Keep away from sources of ignition. Empty containers pose a fire risk, evaporate the residue under a fume hood. Ground all equipment containing material. Do not ingest. Do not breathe dust. Wear suitable protective clothing. In case of insufficient ventilation, wear suitable respiratory equipment. If ingested, seek medical advice immediately and show the container or the label. Avoid contact with skin and eyes.

  Storage

  Light Sensitive. Store in light-resistant containers. Keep container tightly closed. Keep container in a cool, well-ventilated area.

• Section 8 – EXPOSURE CONTROLS / PERSONAL PROTECTION

  Engineering Controls

  Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit.

  Personal Protective Protection

  Splash goggles. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves.

  Personal Protection in case of Large Fire

  Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self-contained breathing apparatus should be used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this product.

  Exposure Limits

  N/A

• Section 9 – PHYSICAL AND CHEMICAL PROPERITIES

  Appearance Form

  Solid

  Odor

  Slight odor.

  Taste

  N/A

  pH

  N/A

  Boiling Point

  N/A

  Melting Point

  N/A

  Critical Temperature

  N/A

  Specific Gravity

  N/A

  Vapor Pressure

  N/A

  Vapor Density

  N/A

  Volatility

  N/A

  Odor Threshold

  N/A

  Water/Oil Dist. Coeff.

  N/A

  Ionicity (in Water)

  N/A

  Partition coefficient (n-octanol/water)

  N/A

  Solubility in water

  N/A

• Section 10 – STABILITY AND REACTIVITY

  Stability

  The product is stable.

  Instability Temperature

  N/A

  Conditions of Instability

  Excess, incompatible materials

  Incompatibility with various substances

  N/A

  Corrosivity

  N/A

  Special Remarks on Reactivity

  N/A

  Special Remarks on Corrosivity

  N/A

  Polymerization

  Will not occur.

• Section 11 – TOXICOLOGICAL INFORMATION

  Routes of Entry

  Inhalation. Ingestion.

  Toxicity to Animals

  Acute oral toxicity (LD50)

  424 mg/kg [Mouse]..

  Chronic Effects on Humans

  N/A

  Other Toxic Effects on Humans

  Hazardous in case of skin contact (irritant), of ingestion, of inhalation.

  Special Remarks on Toxicity to Animals

  N/A

  Acute Potential Health Effects

  Skin

  May cause skin irritation.

  Eyes

  Dust may cause eye irritation.

  Inhalation

  Dust may cause respiratory tract irritation; may affect blood, endocrine system, urinary tract (bladder, ureter).

  Ingestion

  May be harmful if swallowed. May cause gastrointestinal tract irritation. May affect Central Nervous System, behavior (ataxia, spasticity, convulsions, muscle weakness, somnolence (general depressed activity).

• Section 12 – ECOLOGICAL INFORMATION

  Toxicity

  N/A

  BOD5 & COD

  N/A

  Products of Biodegradation

  Possibly hazardous short term degradation products are not likely. However, long term degradation products may arise.

  Toxicity of the Products of Biodegradation

  The products of degradation are as toxic as the product itself.

• Section 13 – DISPOSAL CONSIDERATION

  No data available.

• Section 14 – TRANSPORT INFORMATION

  DOT Classification

  Not a DOT controlled material (United States).

  Identification

  N/A

  Special Provisions for Transport

  N/A

• Section 15 – REGULATORY INFORMATION

  Federal and State Regulations

  TSCA 8(b) inventory

  Trifluoperazine Hydrochloride

  Other Regulations

  OSHO

  Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200).

  EINECS

  This product is on the European Inventory of Existing Commercial Chemical Substances.

  Other Regulations

  WHMIS (Canada)

  Not controlled under WHMIS (Canada).

  DSCL (EEC)

  R22

  Harmful if swallowed.

  R36/38

  Irritating to eyes and skin.

  S22

  Keep out of the reach of children.

  S46

  If swallowed, seek medical advice immediately and show this container or label.

  HMIS (U.S.A.)

  Health Hazard

  2

  Fire Hazard

  1

  Reactivity

  0

  Personal Protection

  E

  National Fire Protection Association (U.S.A.)

  Health

  2

  Flammability

  1

  Reactivity

  0

  Specific hazard

  Protective Equipment

  Gloves. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Wear appropriate respirator when ventilation is inadequate. Splash goggles.

• Section 16 – OTHER INFORMATION

  Global Pharma provides information contained herein in good faith but makes no representation as to its comprehensives or accuracy. This document is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product.

  Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose.

  GLOBAL PHARMA MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESSED OR IMPLIED, INCLUDING WITHOUT LIMITATION ANY WARRANTIES OR MERCHANTABILITY, FITNESS FOR A PARTICULER PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH HEREIN OR THE PRODUCT WHICH THE INFORMATION REEFERS. GLOBAL PHARMA WILL NOT BE RESPONSIBLE FOR DAMAGES RESULTING FROM USE OF RELIANCE UPON THIS INFORMATION.