Chlorhexidine is an antiseptic that fights bacteria.

Chlorhexidine topical (for the skin) is used to clean the skin to prevent infection that may be caused by surgery, injection, or skin injury.

Chlorhexidine topical may also be used for purposes not listed in this medication guide.

 

Certificate of Analysis

• Description

  An almost colourless or pale-yellowish, clear or slightly opalescent liquid; almost odourless.

  Result

  An almost colourless liquid.

• Identification by IR

  Should match with the standard.

  Result

  Complies

• Identification by Reaction of chlorides

  To match with the reference standard.

  Result

  Complies

• Identification by TLC

  Principal spot should match with reference.

  Result

  Complies

• Weight per ml.

  Between 1.06 to 1.07 determined at 20° C

  Result

  1.063

• pH

  Dilute 5.0ml to 100.0ml with carbon dioxide free water R. The pH of solution is 5.5 to 7.0

  Result

  5.89

• Chloroaniline

  As per IP

  Result

  Complies

• Related substance

  As per IP

  Result

  Complies

• Assay

  Chlorhexidine gluconate solution contains not less than 19.0 % w/v. & not more than 21.0 % w/v. Of C22H30CL2N10,2C6H12O7.

  Result

  20.5 %w/v.

• Colour test

  Absorbance not more than 0.03 at 480 nm

  Result

  0.009 Abs.

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Material Safety Data Sheet

• Section 1 – Chemical Product

  Product Identifier

  Chlorhexidine Gluconate

  MSDS Prepared By

  R&D Department

• Section 2 – Composition / Information Of Ingredients

  Product Name

  Chlorhexidine Gluconate

  Synonym

  Biguanide, 1,1- Hexamethyle & Digluconate (5-(p-Chlorophenyl)- Digluconate ‘1.6-nis (5(p-Chlorophenyl))- Digluconate

  CAS Number

  18472-51-0

• Section 3 – HAZARDOUS IDENTIFICATION

  General Information

  Irritating to eye and skin. Very toxic to aquatic organisms. May cause long term adverse effects in the aquatic environment.

• Section 4 – FIRST AID

  Inhalation

  Mover to fresh air.

  Skin Contact

  Remove contaminated clothing. Wash effected skin with soap and plenty of water. Seek medical attention.

  Eye Contact

  Immediately flush eyes with water for at least 15 minutes. Seek medical attention.

  Ingestion

  Wash out mouth with water, drink plenty of water.

• Section 5 – FIRE FIGHTING MEASURES

  Equipment for Firefighters

  In case of fire, wear a self-contained breathing apparatus.

  Extinguishing Media

  Use Water, Water Spray, Dry powder, Foam, Carbon dioxide.

• Section 6 – ACCIDENT RELEASE MEASURES

  Personal precautions

  Goggles, gloves.

  Environmental Precautions

  Do not flush into surface water or sanitary sewer system.

• Section 7 – HANDLING AND STORAGE

  Handling

  Avoid ingestion, inhalation, skin and eye contact. Handle in accordance with good industrial hygiene practice and any legal requirements.

  Storage

  Keep container tightly closed in a dry and well-ventilated place. Sensitive to heat over 400C.

• Section 8 – EXPOSURE CONTROLS / PERSONAL PROTECTION

  Engineering Controls

  Ensure adequate ventilation especially in confined areas.

  Personal Protection

  Respiratory protection

  Effective dust mask.

  Hand protection

  Gloves

  Eye Protection

  Goggles

  Skin and body protection

  Lightweight protective clothing.

  Hygiene measures

  Keep away from food, drink and animal feeding stuffs shower or bathe at the working.

• Section 9 – PHYSICAL AND CHEMICAL PROPERITIES

  Appearance

  Liquid

  Boiling Point

  ~97°C

  Specific Gravity

  1.06 to 1.07

  Solubility

  Water – Miscible, ethanol – Miscible. Acetone – Miscible

• Section 10 – STABILITY AND REACTIVITY

  Chemical Stability

  Stable

  Conditions to avoid

  Exposure to sunlight.

  Material to avoid

  Avoid contact with chlorinating substances.

  Hazardous Decomposition Products

  None under normal storage condition.

• Section 11 – TOXICOLOGICAL INFORMATION

  Acute Toxicity

  (LD 50) 45 g/kg Rat (oral)

  Primary Irritation

  (Skin) Irritant EC 83 Rabbit

  Adverse Effects

  (Eye) Irritant EC 83 Rabbit

• Section 12 – ECOLOGICAL INFORMATION

  Toxicity

  No additional Information available

  Persistence and degradability

  No additional Information available

  Bioaccumulative potential

  No additional Information available

  Mobility in soil

  No additional Information available

  Other adverse effects

  Effect on Ozone Layer

  No additional Information available.

  Effect on the Global Warming

  No known ecological damage caused by this product.

• Section 13 – DISPOSAL CONSIDERATION

  Waste Disposal

  Dissolve or mix the material with a combustible solvent and burn. In a chemical incinerator equipped with an afterburner and Scrubber. Observe all federal, staff and local environmental Regulations.

• Section 14 – TRANSPORT INFORMATION

  Non-hazardous.

• Section 15 – REGULATORY INFORMATION

  Classification and labeling as per local federal, staff regulations.

• Section 16 – OTHER INFORMATION

  Global Pharma provides information contained herein in good faith but makes no representation as to its comprehensives or accuracy. This document is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product.

  Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose.

  GLOBAL PHARMA MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESSED OR IMPLIED, INCLUDING WITHOUT LIMITATION ANY WARRANTIES OR MERCHANTABILITY, FITNESS FOR A PARTICULER PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH HEREIN OR THE PRODUCT WHICH THE INFORMATION REEFERS. GLOBAL PHARMA WILL NOT BE RESPONSIBLE FOR DAMAGES RESULTING FROM USE OF RELIANCE UPON THIS INFORMATION.